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1

Pharmacology and Pharmacokinetics of Minoxidil

Lowenthal, David T., Affrime, Melton B.

Journal:

Journal of Cardiovascular Pharmacology

Year:

1980

File:

PDF, 566 KB

1980

2

Pharmacokinetics of loratadine and pseudoephedrine following single and multiple doses of once- versus twice-daily combination tablet formulations in healthy adult males

Teddy Kosoglou, Elaine Radwanski, Vijay K. Batra, Josephine M. Lim, David Christopher, Melton B. Affrime

Journal:

Clinical Therapeutics

Year:

1997

Language:

english

File:

PDF, 660 KB

english, 1997

3

Effect of Ethanol on Metabolic Responses to Treadmill Running in Well-Trained Men

Kendrick, Zebulon V., Affrime, Melton B., Lowenthal, David T.

Journal:

Journal of Clinical Pharmacology

Year:

1993

Language:

english

File:

PDF, 588 KB

english, 1993

4

Pharmacokinetics of Interferon α-2b in Healthy Volunteers

Radwanski, Elaine, Perentesis, George, Jacobs, Sheila, Oden, Edwin, Affrime, Melton, Symchowicz, Samson, Zampaglione, Nicola

Journal:

Journal of Clinical Pharmacology

Year:

1987

Language:

english

File:

PDF, 651 KB

english, 1987

5

Pharmacodynamics of subcutaneous recombinant human interleukin-10 in healthy volunteers*

Huhn, Richard D., Radwanski, Elaine, Gallo, Jose, Affrime, Melton B., Sabo, Ron, Gonyo, Gerilyn, Monge, April, Cutler, David L.

Journal:

Clinical Pharmacology & Therapeutics

Year:

1997

Language:

english

File:

PDF, 1.58 MB

english, 1997

6

The Effect of Antacid and Cimetidine on the Oral Absorption of the Antifungal Agent SCH 39304

Kosoglou, Teddy, Perentesis, George P., Affrime, Melton B., Lin, Chin-Chung, Mojaverian, Parviz, Radwanski, Elaine, Vlasses, Peter H.

Journal:

Journal of Clinical Pharmacology

Year:

1990

Language:

english

File:

PDF, 740 KB

english, 1990

7

Cardiovascular Safety of Second-Generation Antihistamines

Barbey, Jean-Thierry, Anderson, Mark, Ciprandi, Giorgio, Frew, Anthony J., Morad, Martin, Priori, Silvia G., Ongini, Ennio, Affrime, Melton B.

Journal:

American Journal of Rhinology

Year:

1999

Language:

english

File:

PDF, 2.84 MB

english, 1999

8

Timolol kinetics in chronic renal insufficiency

Lowenthal, David T., Pitone, Joseph M., Affrime, Melton B., Shirk, Jane, Busby, Patricia, Kim, Kwan E., Nancarrow, John, Swartz, Charles D., Onesti, Gaddo

Journal:

Clinical Pharmacology & Therapeutics

Year:

1978

Language:

english

File:

PDF, 1.15 MB

english, 1978

9

Influence of uremia, hemodialysis, and nonesterified fatty acids on zomepirac plasma protein binding

Pritchard, J Frederick, O'Neill, Patrick J, Affrime, Melton B, Lowenthal, David T

Journal:

Clinical Pharmacology & Therapeutics

Year:

1983

Language:

english

File:

PDF, 574 KB

english, 1983

10

Effects of amiloride on oral glucose loading, serum potassium, renin, and aldosterone in diet-controlled diabetes

Lowenthal, David T, Gould, Anne, Shirk, Jane, Mazzella, Jane, Affrime, Melton B, Walker, Findlay, Onesti, Gaddo

Journal:

Clinical Pharmacology & Therapeutics

Year:

1980

Language:

english

File:

PDF, 311 KB

english, 1980

11

A Systemic Bioactivity Comparison of Double-Strength and Regular-Strength Beclomethasone Dipropionate MDI Formulations

Brannan, Melvin D, Herron, Jerry M, Reidenberg, Pascale, Affrime, Melton B

Journal:

Annals of Allergy, Asthma & Immunology

Year:

1998

Language:

english

File:

PDF, 209 KB

english, 1998

12

Comparative Pharmacokinetics of Oral Ceftibuten, Cefixime, Cefaclor, and Cefuroxime Axetil in Healthy Volunteers

Dr. David E. Nix, Dr. William T. Symonds, Dr. Judith M. Hyatt, Dr. John H. Wilton, Dr. Marilyn A. Teal, Dr. Pascale Reidenberg, Dr. Melton B. Affrime

Journal:

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

Year:

1997

Language:

english

File:

PDF, 471 KB

english, 1997

13

Pharmacokinetic equivalence of pediatric dosages of desloratadine syrup in children and standard 5-mg desloratadine tablets in adults

Banfield, Christopher, Gupta, Samir, Affrime, Melton, Batra, Vijay

Journal:

Journal of Allergy and Clinical Immunology

Year:

2002

Language:

english

File:

PDF, 134 KB

english, 2002

14

Moorland Waters and Lead Poisoning.

Brannan, Melvin D, Herron, Jerry M, Reidenberg, Pascale, Affrime, Melton B

Journal:

Year:

1903

Language:

english

File:

PDF, 319 KB

english, 1903

15

Single-dose pharmacokinetics and tolerability of pegylated interferon-α2b in young and elderly healthy subjects

Samir K. Gupta, Paul Glue, Sheila Jacobs, Donna Belle, Melton Affrime

Journal:

British Journal of Clinical Pharmacology

Year:

2003

Language:

english

File:

PDF, 93 KB

english, 2003

16

Grapefruit Juice Reduces the Oral Bioavailability of Fexofenadine But Not Desloratadine

Dr Christopher Banfield, Samir Gupta, Mark Marino, Josephine Lim, Melton Affrime

Journal:

Clinical Pharmacokinetics

Year:

2002

Language:

english

File:

PDF, 146 KB

english, 2002

17

Pharmacokinetics and Leukocyte Responses of Recombinant Human Interleukin-10

Elaine Radwanski, Abhijit Chakraborty, Scott Van Wart, Richard D. Huhn, David L. Cutler, Melton B. Affrime, William J. Jusko

Journal:

Pharmaceutical Research

Year:

1998

File:

PDF, 614 KB

1998

18

Influence of Food on the Oral Bioavailability of Loratadine and Pseudoephedrine from Extended-Release Tablets in Healthy Volunteers

Nomeir, Amin A., Mojaverian, Parviz, Kosoglou, Teddy, Affrime, Melton B., Nezamis, Jim, Radwanski, Elaine, Lin, Chin-Chung, Cayen, Mitchell N.

Journal:

Journal of Clinical Pharmacology

Year:

1996

Language:

english

File:

PDF, 1.32 MB

english, 1996

19

Regional lung deposition of a technetium 99m-labeled formulation of mometasone furoate administered by hydrofluoroalkane 227 metered-dose inhaler

Hannah Pickering, Gary R. Pitcairn, Peter H. Hirst, Rachel E. Bacon, Stephen P. Newman, Melton B. Affrime, Mark Marino

Journal:

Clinical Therapeutics

Year:

2000

Language:

english

File:

PDF, 707 KB

english, 2000

20

The Diuretic Response in Normal Volunteers To a New Benzylamine, 2-Aminomethyl-4-(1,1-dimethylethyl)-6-iodophenol HCI

LOWENTHAL, DAVID T., ONESTI, GADDO, AFFRIME, MELTON B., SCHROGIE, JOHN J., KIM, KWAN E., BUSBY, PATRICIA, SWARTZ, CHARLES D.

Journal:

Journal of Clinical Pharmacology

Year:

1978

Language:

english

File:

PDF, 967 KB

english, 1978

21

Biochemical and dynamic responses to single and repeated doses of methyldopa and propranolol during dynamic physical activity

Rosenthal, Leslie, Affrime, Melton B, Lowenthal, David T, Falkner, Bonita, Saris, Steve, Gould, Anne B

Journal:

Clinical Pharmacology & Therapeutics

Year:

1982

Language:

english

File:

PDF, 541 KB

english, 1982

22

Pharmacodynamic interaction between the new selective cholesterol absorption inhibitor ezetimibe and simvastatin

Teddy Kosoglou, Ingo Meyer, Enrico P. Veltri, Paul Statkevich, Bo Yang, Yali Zhu, Lillian Mellars, Stephen E. Maxwell, James E. Patrick, David L. Cutler, Vijay K. Batra, Melton B. Affrime

Journal:

British Journal of Clinical Pharmacology

Year:

2002

Language:

english

File:

PDF, 128 KB

english, 2002

23

Differential plasma duration of antiplatelet-activating factor and antihistamine activities of oral Sch 37370 in humans

Billah, M Motasim, Gilchrest, Helen G, Eckel, Stephen P, Granzow, Catherine A, Lawton, Paul J, Radwanski, Elaine, Brannan, Melvin D, Affrime, Melton B, Christopher, J David, Richards, Winston

Journal:

Clinical Pharmacology & Therapeutics

Year:

1992

Language:

english

File:

PDF, 584 KB

english, 1992

24

Stepwise determination of multicompartment disposition and absorption parameters from extravascular concentration-time data. Application to mesoridazine, flurbiprofen, flunarizine, labetalol, and diazepam

John G. Wagner, Derek A. Ganes, Kamal K. Midha, Iraida Gonzalez-Younes, J. Chris Sackellares, Larry D. Olson, Melton B. Affrime, James E. Patrick

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

1991

Language:

english

File:

PDF, 1.94 MB

english, 1991

25

Loratadine administered concomitantly with erythromycin: Pharmacokinetic and electrocardiographic evaluations*

Brannan, Melvin D., Reidenberg, Pascale, Radwanski, Elaine, Shneyer, Lucy, Lin, Chin-Chung, Cayen, Mitchell N., Affrime, Melton B.

Journal:

Clinical Pharmacology & Therapeutics

Year:

1995

Language:

english

File:

PDF, 942 KB

english, 1995

26

Desloratadine Demonstrates Dose Proportionality in Healthy Adults After Single Doses

Samir Gupta, Christopher Banfield PhD, Melton Affrime…

Journal:

Clinical Pharmacokinetics

Year:

2002

Language:

english

File:

PDF, 118 KB

english, 2002

27

Clinical, hematologic, and immunologic effects of interleukin-10 in humans

Amy C. Fuchs, Eric V. Granowitz, Leland Shapiro, Edouard Vannier, Gerhard Lonnemann, Jonathan B. Angel, Jeffrey S. Kennedy, Arthur R. Rabson, Elaine Radwanski, Melton B. Affrime, David L. Cutler, Paul

Journal:

Journal of Clinical Immunology

Year:

1996

Language:

english

File:

PDF, 1.00 MB

english, 1996

28

Safety and tolerability of once-daily mometasone furoate aqueous nasal spray in children

Melvin D. Brannan, Jerry M. Herron, Melton B. Affrime

Journal:

Clinical Therapeutics

Year:

1997

Language:

english

File:

PDF, 498 KB

english, 1997

29

Oral Bioavailability of Desloratadine Is Unaffected by Food

Samir Gupta, Christopher Banfield PhD, Melton Affrime…

Journal:

Clinical Pharmacokinetics

Year:

2002

Language:

english

File:

PDF, 116 KB

english, 2002

30

Effects of Clonidine and Hydrochlorothiazide on the Cardiovascular Response to Mental Stress in Adolescent Hypertension

Falkner, Bonita, Onesti, Gaddo, Affrime, Melton B., Lowenthal, David T.

Journal:

Clinical Science

Year:

1982

Language:

english

File:

PDF, 285 KB

english, 1982

31

Disposition of 14C-eptifibatide after intravenous administration to healthy men

Kevin B. Alton, Teddy Kosoglou, Susan Baker, Melton B. Affrime, Mitchell N. Cayen, James E. Patrick

Journal:

Clinical Therapeutics

Year:

1998

Language:

english

File:

PDF, 1.06 MB

english, 1998

32

Prazosin kinetics and effectiveness in renal failure

Lowenthal, David T, Hobbs, Donald, Affrime, Melton B, Twomey, Thomas M, Martinez, Eduardo W, Onesti, Gaddo

Journal:

Clinical Pharmacology & Therapeutics

Year:

1980

Language:

english

File:

PDF, 310 KB

english, 1980

33

A Pharmacokinetic Profile of Desloratadine in Healthy Adults, Including Elderly

Melton Affrime, Samir Gupta, Christopher Banfield PhD…

Journal:

Clinical Pharmacokinetics

Year:

2002

Language:

english

File:

PDF, 130 KB

english, 2002

34

The pharmacokinetics of ceftibuten in humans

Barr, William H., Lin, Chin-Chung, Radwanski, Elaine, Lim, Josephine, Symchowicz, Samson, Affrime, Melton

Journal:

Diagnostic Microbiology and Infectious Disease

Year:

1991

Language:

english

File:

PDF, 706 KB

english, 1991

35

Potassium Disposition and Neuroendocrine Effects of Propranolol, Methyldopa and Clonidine During Dynamic Exercise

Lowenthal, David T., Affrime, Melton B., Falkner, Bonita, Saris, Steven, Hakki, Hamid, Rosenthal, Leslie

Journal:

Clinical and Experimental Hypertension

Year:

1982

Language:

english

File:

PDF, 633 KB

english, 1982

36

Effect of Race and Sex on Single and Multiple Dose Pharmacokinetics of Desloratadine

Melton Affrime, Christopher Banfield PhD, Samir Gupta…

Journal:

Clinical Pharmacokinetics

Year:

2002

Language:

english

File:

PDF, 137 KB

english, 2002

37

Pharmacokinetic Drug Interaction Study

Radwanski, Elaine, Nomeir, Amin, Lin, Chin-Chung, Cutler, David, Affrime, Melton

Journal:

American Journal of Therapeutics

Year:

1998

File:

PDF, 460 KB

1998

38

Pharmacokinetics and Pharmacodynamics of Clonidine in Varying States of Renal Function

Lowenthal, David T., Affrime, Melton B., Meyer, Alan, Kim, Kwan E., Falkner, Bonita, Sharif, Kurosh

Journal:

Year:

1983

Language:

english

File:

PDF, 2.74 MB

english, 1983

39

Pharmacokinetics and pharmacodynamics of dilevalol

Tenero, David M, Bottorff, Michael B, Given, Bruce D, Kramer, William G, Affrime, Melton B, Patrick, James E, Lalonde, Richard L

Journal:

Clinical Pharmacology & Therapeutics

Year:

1989

Language:

english

File:

PDF, 571 KB

english, 1989

40

The pharmacokinetics, electrocardiographic effects, and tolerability of loratadine syrup in children aged 2 to 5 years

Luis M. Salmun, Jerry M. Herron, Christopher Banfield, Desmond Padhi, Richard Lorber, Melton B. Affrime

Journal:

Clinical Therapeutics

Year:

2000

Language:

english

File:

PDF, 625 KB

english, 2000

41

Dynamic and biochemical responses to single and repeated doses of clonidine during dynamic physical activity

Lowenthal, David T, Affrime, Melton B, Rosenthal, Leslie, Gould, Anne B, Borruso, John, Falkner, Bonita

Journal:

Clinical Pharmacology & Therapeutics

Year:

1982

Language:

english

File:

PDF, 395 KB

english, 1982

42

Effectiveness of centrally acting drugs and diuretics in adolescent hypertension

Falkner, Bonita, Onesti, Gaddo, Lowenthal, David T, Affrime, Melton B

Journal:

Clinical Pharmacology & Therapeutics

Year:

1982

Language:

english

File:

PDF, 314 KB

english, 1982

43

Ceftibuten in Paediatrics

Robert D. Colucci,Michael Elliott,Melton B. Affrime…

Journal:

Clinical Pharmacokinetics

Year:

1994

Language:

english

File:

PDF, 395 KB

english, 1994

44

Mometason Furoate Levels

Affrime, Melton B.

Journal:

Year:

2001

Language:

english

File:

PDF, 55 KB

english, 2001

45

QT and QTc Interval With Standard and Supratherapeutic Doses of Darifenacin, a Muscarinic M 3 Selective Receptor Antagonist for the Treatment of Overactive Bladder

Serra, Denise B., Affrime, Melton B., Bedigian, Martin P., Greig, Gerard, Milosavljev, Slavica, Skerjanec, Andrej, Wang, Yibin

Journal:

Journal of Clinical Pharmacology

Year:

2005

Language:

english

File:

PDF, 141 KB

english, 2005

46

Interleukin-10 Inhibits Activation of Coagulation and Fibrinolysis During Human Endotoxemia

Pajkrt, Dasja, van der Poll, Tom, Levi, Marcel, Cutler, David L., Affrime, Melton B., van den Ende, Abraham, Wouter ten Cate, Jan, J.H. van Deventer, Sander

Journal:

Year:

1997

File:

PDF, 177 KB

1997

47

Pharmacokinetics of dilevalol in normotensive and hypertensive volunteers

William G. Kramer, George Perentesis, Melton B. Affrime, James E. Patrick

Journal:

The American Journal of Cardiology

Year:

1989

Language:

english

File:

PDF, 367 KB

english, 1989

48

Pharmacokinetic and safety profile of desloratadine and fexofenadine when coadministered with azithromycin: a randomized, placebo-controlled, parallel-group study

Samir Gupta, Christopher Banfield, Bhavna Kantesaria, Mark Marino, Robert Clement, Melton Affrime, Vijay Batra

Journal:

Clinical Therapeutics

Year:

2001

Language:

english

File:

PDF, 963 KB

english, 2001

49

Mometasone Furoate Has Minimal Effects on the Hypothalamic-Pituitary-Adrenal Axis When Delivered at High Doses

Affrime, Melton B., Kosoglou, Teddy, Thonoor, C. Mohan, Flannery, Brian E., Herron, Jerry M.

Journal:

Year:

2000

Language:

english

File:

PDF, 297 KB

english, 2000

50

Pharmacokinetics of ceftibuten in children

BARR, WILLIAM H., PHARMD,, AFFRIME, MELTON, PHARMD,, LIN, CHIN-CHUNG, BATRA, VIJAY

Journal:

Pediatric Infectious Disease Journal

Year:

1995

File:

PDF, 698 KB

1995

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